Rat Anti-Mouse VEGF-A

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Cat-Nr.103-M57
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#2G02)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with mouse VEGF164 recombinant protein). The IgG2 fraction of culture supernatant was purified by Protein G affinity chromatography.
Antigenrecombinant mouse VEGF-A
ApplicationWB, IHC
SynonymsVegfa; Vpf; Vegf; Vegf120; Vegf164; Vegf188
DescriptionMouse VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains.
Uniprot IDQ00731
Protein RefSeqNP_001020421
mRNA RefSeqNM_001025250

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