Mouse Anti-Human CD244

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#7D24)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human CD244 recombinant protein (extracellular domain).
AntigenHuman recombinant CD244 (EC domain)
SynonymsCD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Description2B4, also known as CD244, is a cell surface glycoprotein belonging to the CD2 subgroup of the immunoglobulin superfamily. It acts as a high-affinity receptor for CD48. It is expressed by natural killer (NK) cells and CD8+ T cell subsets. It can regulate killing by CD8+ T cells and NK cells, and IFN-gamma secretion by NK cells. It may also regulate NK cell and T cell proliferation.
Uniprot IDQ9BZW8
Protein RefSeqNP_057466
mRNA RefSeqNM_016382

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