Mouse Anti-Human IFN alpha

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Cat-Nr.101-M771
Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#8U18
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationProduced in BALB/c x ICR F1 mice using recombinant human IFN- as the immunizing antigen. IgG1 antibody was purified from ascites fluid on a Protein A affinity column.
Antigen Human recombinant IFN alpha
ApplicationWB, N/B, IHC (F)
SynonymsIFNA1; IFL; IFN; IFNA; IFNA13; IFN-ALPHA; IFN-alphaD; Interferon
DescriptionInterferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
Uniprot IDP01562
Protein RefSeqNP_076918.1
mRNA RefSeqNM_024013.1

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