Mouse Anti-Human DRAK2

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Cat-Nr.101-M593
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#4U29)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenRecombinant human DRAK2
ApplicationWB
SynonymsSerine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2
DescriptionSTK17B (also known as DRAK2) is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis. STK17B is selectively important for T-cell survival and inhibition of STK17B has therapeutic potential for autoimmune disease. T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of STK17B can affect autoimmune disease susceptibility without generalized suppression of the immune system.
Uniprot IDO94768
Protein RefSeqNP_004217.1
mRNA RefSeqNM_004226.3

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