Mouse Anti-Human TGFR-1 (ALK-1)

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Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#8G33)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with purified human extracellular domain of ALK1. The IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography.
Antigenhuman TGF RI (ALK1) EC domain
ApplicationWB, IHC
SynonymsHHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; ACVRL1; activin A receptor type II-like 1
DescriptionALKs 1-7 are type I serine/threonine kinase receptors for TGF-beta superfamily members. They undergo hetero-oligomerization with type II serine/threonine kinase receptors to transduce signals, usually through Smad proteins. Alk-1 binds TGF-beta and Alk-7 is thought to bind nodal.
Uniprot IDP37023
Protein RefSeqNP_000011.2
mRNA RefSeqNM_000020.2

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