Hamster Anti-Mouse CD3e

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Cat-Nr.103-M516
Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#1T29)
IsotypeIgG
AntigenRecombinant mouse CD3e
ApplicationFC, IP
SynonymsT-cell surface antigen T3/Leu-4 epsilon chain
DescriptionThe protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women
Uniprot IDP22646
Protein RefSeqNP_031674.1
mRNA RefSeqNM_007648.4

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