Mouse Anti-Human TIE-1

Slide this table

Cat-Nr.101-M46
Size100 µg
Price230 €
CategoryMonoclonal Antibody
Clone Nr.(#8C9)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
PreparationThe monoclonal antibody was produced with the help of BALB/c mice using recombinant human soluble extracellular TIE-1 as the immunizing antigen. Mouse IgG1 antibody (#8C9) from hybridomas was purified from cell culture supernatant by Protein G chromatography.
Antigenrecombinant human soluble TIE-1
ApplicationELISA, WB
SynonymsTIE1; TIE; JTK14
DescriptionTIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.
Uniprot IDP35590
Protein RefSeqNP_005415
mRNA RefSeqNM_005424

Figures


All prices plus VAT + possible delivery charges