Mouse Anti-Human Transferrin R

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Cat-Nr.101-M765
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7W11)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TfR extracellular domain.
AntigenHuman recombinant TfR EC domain
ApplicationFC
SynonymsTFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR
DescriptionTransferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.
Uniprot IDP02786
Protein RefSeqNP_003225.2
mRNA RefSeqNM_003234.2

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