Mouse Anti-Human Megalin

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Size100 µg
Price275 €
CategoryMonoclonal Antibody
Clone Nr.(#CD7D5)
Species ReactivityHuman, rat, mouse
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
PreparationMonoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.
Antigenpurified human Megalin
ApplicationIHC; IF
SynonymsLRP2; DBS; GP330; low density lipoprotein receptor-related protein 2; Glycoprotein 330
DescriptionMegalin/gp330, an approx. 600 kDa transmembrane glycoprotein is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease:protease inhibitor families.
Uniprot IDP98164
Protein RefSeqNP_004516.2
mRNA RefSeqNM_004525.2



  1. NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells. Yujiro Maeoka et al., J Biol Chem. 2019 Jan 4; 294(1): 101–115.

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