Mouse Anti-Human ALPL

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#4C67)
Species ReactivityHuman
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenNative human ALPL
SynonymsAlkaline phosphatase, tissue-nonspecific isozyme, AP-TNAP; TNS-ALP, Phosphocreatine phosphatase
DescriptionThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on chromosome 2, whereas the tissue-nonspecific form is located on chromosome 1. The product of this gene is a membrane-bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization. However, mice that lack a functional form of this enzyme show normal skeletal development.
Uniprot IDP05186
Protein RefSeqNP_000469.3
mRNA RefSeqNM_000478.5

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