Rat Anti-Mouse GFR 4 alpha

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Cat-Nr.103-M394
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#1M21)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of GFR4a.
Antigenrecombinant mouse protein GFR alpha 4
ApplicationELISA, IHC (F)
SynonymsGfra4; AW060733; G630015H18Rik
DescriptionGFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins.
Uniprot IDQ9JJT2
Protein RefSeqNP_064398.1
mRNA RefSeqNM_020014

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