Rat Anti-Mouse SCF-R

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Cat-Nr.103-M194
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#9D2)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified recombinant mouse SCF-R extracellular domain. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography.
Antigenrecombinant mouse SCF-R EC domain
ApplicationWB, IHC
SynonymsKit; W; Bs; Fdc; Ssm; SCO1; SCO5; SOW3; CD117; c-KIT; Tr-kit; Gsfsco1; Gsfsco5; Gsfsow3
DescriptionStem cell factor receptor (CD117, the gene product of the c-kit proto-oncogene) and its ligand, stem cell factor, play essential roles in gametogenesis, melanogenesis and hematopoiesis. Stem cell factor receptor is a member of the type III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, Flt-3 and PDGF. It is expressed in hematopoietic progenitor cells, normal B and T cell progenitor cells, mast cells, germ cells, melanocytes, neurons, glial cells, placenta, kidney, lung and gut.
Uniprot IDP05532
Protein RefSeqNP_001116205.1
mRNA RefSeqNM_001122733.1

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