Mouse Anti-Human NCAM-L1

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#1J36)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NCAM-L1, also called CD171.
Antigenhuman recombinant protein of NCAM-L1 EC domain
SynonymsL1CAM; S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
DescriptionThe cell adhesion molecule NCAM-L1 (or L1CAM) is an immunoglobulin superfamily adhesion molecule that is critical for neural development. Two alternatively spliced isoforms of L1CAM have been described. The full-length signaling isoform is expressed exclusively in neurons. The second non-neuronal variant lacks a five-residue extracellular sequence and a four residue cytoplasmic sequence that is important in signaling and clathrin-mediated endocytosis.
Uniprot IDP32004
Protein RefSeqNP_000416.1
mRNA RefSeqNM_000425.4

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