Mouse Anti-Human IL-10 receptor beta

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#8R24)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-10 Rb extracellular domain.
Antigenrecombinant human IL-10 Rbeta EC domain
ApplicationWB, N
SynonymsIL10RB; CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2
DescriptionIL-10 mediates its biological activities via binding to a heteromeric complex of two distinct type II cytokine receptor subunits, the ligand binding subunit IL-10 R alpha (IL-10 R1) and the signal-transducing accessory subunit IL-10 R beta (IL-10 R2). IL-10 R alpha is specific for IL-10 and expressed by most hemopoietic cells. IL-10 R beta is a widely expressed shared subunit for IL-10, IL-22, IL-26 and the IFNl proteins IL-28A, IL-28B and IL-29.
Uniprot IDQ08334
Protein RefSeqNP_000619.3
mRNA RefSeqNM_000628.4

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