Mouse Anti-Human TNFSF10

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#6D44)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human TNFSF10 recombinant protein (also called TRAIL).
Antigenrecombinant human TNFSF10
ApplicationN, IHC (P), FC
SynonymsTNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
DescriptionTNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members. Among TNF superfamily members, TRAIL is the most homologous to Fas Ligand, sharing 28% amino acid sequence identity in their extracellular domains. Human TRAIL shares 65% amino acid sequence identity with mouse TRAIL and is active on mouse cells.
Uniprot IDP50591
Protein RefSeqNP_00380.1
mRNA RefSeqNM_003810.3

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