Mouse Anti-Human CD64

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Cat-Nr.101-M313
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#2Y31)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CD64.
Antigenhuman recombinant CD64
ApplicationIHC, FC
SynonymsFCER2; CD23; FCE2; CD23A; IGEBF; CLEC4J
DescriptionReceptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.
Uniprot IDP12314
Protein RefSeqNP_000557.1
mRNA RefSeqNM_000566.3

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