Mouse Anti-Human CD58

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#8G24)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD58 extracellular domain (also called LFA-3).
Antigenhuman recombinant CD585 extracellular domain
ApplicationWB, FC
SynonymsCD58; ag3; LFA3; LFA-3
DescriptionCD58, also known as lymphocyte function-associated antigen (LFA-3) is a cell-bound immunoglobulin superfamily receptor with only one known ligand, CD2. CD58 is widely expressed on human hematopoietic and non-hematopoietic tissues, leukocytes, erythrocytes, endothelial and epithelial cells, and fibroblasts. The engagement of CD58 with CD2 optimizes immune recognition and initiates T cell expansion and activation. These contact activities can occur between helper T cells and antigen-presenting cells and cytolytic effectors and target cells.
Uniprot IDP19256
Protein RefSeqNP_001770.1
mRNA RefSeqNM_001779.2

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