Mouse Anti-Human Coagulation Factor XI

Slide this table

Cat-Nr.101-M332
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7C38)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Coagulation factor XI.
AntigenHuman recombinant Coagulation factor XI
ApplicationWB, N
SynonymsF11; FXI
DescriptionCoagulation Factor XI is synthesized in the liver and circulates in the plasma as a disulfide bond-linked dimer complexed with High Molecular Weight Kininogen. Factor XI is converted into active XIa either via the contact phase of blood coagulation or through Thrombin-mediated activation on the platelet surface. The resulting XIa converts Coagulation Factor IX into IXa, which subsequently activates Coagulation Factor X (Xa). Xa then can mediate Coagulation Factor II/Thrombin activation. Patients with factor XI deficiency are prone to excessive bleeding after hemostatic challenge.
Uniprot IDP03951
Protein RefSeqNP_000119.1
mRNA RefSeqNM_000128.3

All prices plus VAT + possible delivery charges