Mouse Anti-Human IFN alpha/beta Receptor 1

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Cat-Nr.101-M512
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8H46)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of INFa/b RI extracellular domain.
Antigenrecombinant human INF alpha/beta R1 EC domain
ApplicationWB, FC
SynonymsIFNAR1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; Interferon receptor
DescriptionIFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs. IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation.
Uniprot IDP17181
Protein RefSeqNP_000620.2
mRNA RefSeqNM_000629.2

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