Mouse Anti-Human Serpin E1

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Cat-Nr.101-M828
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#12V3)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenHuman recombinant Serpin-E1
ApplicationWB, N/B
SynonymsPlasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, PAI, PAI-1
DescriptionThe human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Uniprot IDP05121
Protein RefSeqNP_000593.1
mRNA RefSeqNM_000602.4

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