Mouse Anti-Human Angiostatin

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Cat-Nr.101-M220
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6F34)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Kringle 1-3 recombinant protein.
Antigenrecombinant human Kringle 1-3
ApplicationWB
SynonymsAngiostatin
DescriptionAngiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Uniprot IDP00747
Protein RefSeqNP_000292.1
mRNA RefSeqNM_000301.3

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