Mouse Anti-Human Nidogen-1 (Entactin)

Slide this table

Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#2R33)
Species ReactivityHuman
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenRecombinant Human Nidogen-1/Entactin
ApplicationEWB, E, IHC
SynonymsNidogen-1, NID-1, Entactin
DescriptionNidogen-1 (also entactin) is a 150 kDa, secreted, monomeric glycoprotein that serves as a major linking component of basement membranes. It is synthesized as a 1247 amino acid (aa) precursor with a 28 aa signal sequence and a 1219 aa mature protein. The molecule is modular in structure with five distinct regions. Functionally, G1 is reported to bind type IV collagen. The mucin region contains a short peptide that ligates alpha 3 beta 1 integrins. G2 interacts with perlecan, and an RGD motif in the rod-shaped segment serves as a binding site for alpha v beta 3 integrins. Finally, G3 is associated with laminin binding.
Uniprot IDP14543
Protein RefSeqNP_002499.2
mRNA RefSeqNM_002508.2

All prices plus VAT + possible delivery charges