Mouse Anti-Human Eotaxin-3

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Size500 µg
Price275 €
CategoryMonoclonal Antibody
IsotypeIgG1, kappa
Species ReactivityHuman
Formulationlyophilized from PBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced in BALB/c mice using recombinant hEotaxin-3 as the immunizing antigen. IgG1/K antibody was purified from ascites fluid on a Protein A affinity column.
AntigenRecombinant Human Eotaxin-3 (CCL26)
ApplicationELISA, WB, N
SynonymsCCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
DescriptionEotaxin3, also named CCL26 or SCYA26, is a novel human CC chemokine that maps to chromosome 7q11.2, within 40 kilobases of the Eotaxin2 loci. Eotaxin3/ CCL26 has been shown to be constitutively expressed in the heart and ovary. In addition, low levels of Eotaxin3/ CCL26 expression can also be detected in various tissues. The expression of Eotaxin 3/CCL26 in vascular endothelial cells has been shown to be upregulated by IL13 and IL4. Eotaxin3/ CCL26 cDNA encodes a 94 amino acid (aa) residue protein with a putative signal peptide of either 23 or 26 aa residues. Eotaxin3/ CCL26 induces calcium flux in eosinophils as well as in CCR3transfected cells. Eotaxin 3/ CCL26 has also been shown to cross-desensitize cells to other CCR3 ligands.
Uniprot IDQ9Y258
Protein RefSeqNP_006063
mRNA RefSeqNM_006072

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