Mouse Anti-Human CD163

Slide this table

Cat-Nr.101-M291
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6J58)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD163 extracellular domain.
AntigenHuman recombinant CD163 EC domain
ApplicationWB, FC
SynonymsCD163; M130; MM130
DescriptionCD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.
Uniprot IDQ86VB7
Protein RefSeqNP_004235.4
mRNA RefSeqNM_004244

All prices plus VAT + possible delivery charges