Rat Anti-Mouse Ly-6G (Gr-1)

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Cat-Nr.103-M206
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#6D17)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with cell lysates of mouse neutrophils. IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenCell lysates of mouse neutrophils
ApplicationFC, IHC (P)
SynonymsLy6g; Gr1; Gr-1; Ly-6G
DescriptionGr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.
Uniprot IDP35461
Protein RefSeqCAA50269.1
mRNA RefSeqXM_001475753.2

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