Rat Anti-Mouse Emilin-1
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| Cat-Nr. | 103-M80 |
| Size | 100 µg |
| Price | 250 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#C11A8) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. |
| Antigen | recombinant mouse Emilin-1 |
| Application | WB, IHC (F) |
| Synonyms | gp115; AW229038; BB105748; EMILIN-1; 5830419M17Rik; elastin microfibril interface located protein 1 |
| Description | Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance. |
| Uniprot ID | Q99K41 |
| Protein RefSeq | NP_598679.1 |
| mRNA RefSeq | NM_133918.2 |
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