Mouse Anti-Human XEDAR protein
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| Cat-Nr. | 101-M861 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#2L23) |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Antigen | Human recombinant XEDAR protein |
| Application | WB, N/B |
| Synonyms | ectodysplasin A2 receptor, EDA2R, EDA-A2 receptor, tumor necrosis factor receptor superfamily member XEDAR, X-linked ectodysplasin-A2 receptor |
| Description | Tumor necrosis factor receptor superfamily member 27 is a protein that in humans is encoded by the EDA2R gene. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. |
| Uniprot ID | Q9HAV5 |
| Protein RefSeq | NP_001186616.1 |
| mRNA RefSeq | NM_001199687.2 |
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