Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2)

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Cat-Nr.103-M230
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7F52)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of the common extracellular domain of HAI-2 isoforms. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigenrecombinant mouse of the common extracellular region of HAI-2 isoforms
ApplicationWB
SynonymsSpint2; HAI-2; C76321; AL024025
DescriptionHAIs (HGF activator inhibitor type 2) belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various human tissues, such as adult placenta, kidney, pancreas, prostate and small intestine, and fetal kidney and lung. It translates into a 478 amino acid protein. The human HAI-2 gene maps to chromosome 19q13.1 and encodes a 252 amino acid protein, also designated human placental bikunin or kop (Kunitz domain containing protein over-expressed in pancreatic cancer). HAI-1 and HAI-2 are produced in membrane-associated forms, which are secreted as active, proteolytically truncated proteins.
Uniprot IDQ9WU03
Protein RefSeqNP_035594.1
mRNA RefSeqNM_011464.2

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