Mouse Anti-Human IFN-gamma Receptor 1

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Cat-Nr.101-M513
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#9U19)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of INFg RI extracellular domain (also called CD119).
Antigenrecombinant human IFN-gamma R1 EC domain
ApplicationWB, FC, N
SynonymsIFNGR1; CD119; IFNGR; Interferon gamma receptor 1;
DescriptionThe high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta). Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.
Uniprot IDP15260
Protein RefSeqNP_000407.1
mRNA RefSeqNM_000416.2

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