Mouse Anti-Human ACE-2

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Cat-Nr.101-M201
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#11A31)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70 °C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human ACE-2 recombinant protein (extracellular domain)
AntigenHuman ACE-2 recombinant protein (extracellular domain)
ApplicationWB, IHC (P)
SynonymsACE2; ACEH
DescriptionThe protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Uniprot IDQ9BYF1
Protein RefSeqNP_068576.1
mRNA RefSeqNM_021804

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