Rat Anti-Mouse Fetuin-A

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#4N42)
Species ReactivityMouse
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Fetuin-A.
Antigenrecombinant mouse Fetuin-A
SynonymsAhsg; fetuin-A
DescriptionMouse Fetuin A, also known as α2-Heremans-Schmid glycoprotein, is encoded by the AHSG gene. It has been also called "countertrypsin" because of its ability to inhibit trypsin. It is a major plasma protein and a member of the cystatin superfamily of protease inhibitors. It is expressed by hepatocytes, the principal cell source, and by monocyte/macrophages. The major form of plasma Fetuin A corresponds to two disulfide bondlinked chains derived from the single chain. FetuinA has a number of functions. It is a negative acutephase protein with normal circulating levels in adults (300-600 μg/mL), which fall significantly (30-50%) during injury and infection. It enhances entry of cationic inhibitors into macrophages. It inhibits both insulin receptor autophosphorylation and undesirable calcification.
Uniprot IDP29699
Protein RefSeqNP_038493.1
mRNA RefSeqNM_013465.2

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