Mouse Anti-Human Resistin

Slide this table

Cat-Nr.101-M170
Size500 µg
Price250 €
CategoryMonoclonal Antibody
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute the antibody in sterile water to a concentration of 1.0mg/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced in BALB/c mice using highly pure (>98%) recombinant human Resistin as the immunizing antigen. This IgG2bK antibody was purified from ascites fluid by Protein A affinity chromatography.
AntigenRecombinant Human Resistin
ApplicationELISA, WB
SynonymsRETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
DescriptionResistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond.
Uniprot IDQ9HD89
Protein RefSeqNP_065148
mRNA RefSeqNM_020415

All prices plus VAT + possible delivery charges