Mouse Anti-Human VE-Cadherin

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Cat-Nr.101-M99
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#8A03)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human VE-Cadherin recombinant protein. The IgG1 fraction of culture supernatant was purified by Protein G affinity chromatography.
Antigenextracellular domain of human VE-Cadherin
ApplicationELISA, WB, IHC
SynonymsCDH5; 7B4; CD144
DescriptionThe antibody reacts with human CD144, also known as VE-cadherin and cadherin-5. The cadherin family of receptors, which are calcium-dependent adhesion molecules, is known to be involved in homophilic cell interactions. VE-cadherin, which is 140 kDa, is localized at the intercellular boundaries of endothelial cells in blood and lymphatic vessels in several tissues. It is thought to play a role in vascular permeability and remodeling.
Uniprot IDP33151
Protein RefSeqNP_001786.2
mRNA RefSeqNM_001795.3

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