Rat Anti-Mouse IL-10

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Cat-Nr.103-M202
Size500 µg
Price250 €
CategoryMonoclonal Antibody
IsotypeIgG1
Species ReactivityMouse
Formulationlyophilized from PBS
BufferPBS
ReconstitutionReconstitute the antibody in sterile water to a concentration of 1.0mh/mL.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced in Sprague Dawley rats using highly pure (>98%) recombinant murine IL-10 as the immunizing antigen. This IgG2A antibody was purified from cell culture by Protein G affinity chromatography.
AntigenRecombinant mouse IL-10
ApplicationWB, N
SynonymsIl10; CSIF; Il-10
DescriptionInterleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of mouse T helper (Th) 2 clones that inhibited cytokine production by Th1 clones . The human ortholog of mouse IL-10 was subsequently cloned by cross-hybridization. Human and mouse IL-10 are 81% identical at the nucleotide and amino acid level. IL-10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. A number of viruses, including Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), also encode viral members of the IL-10 family. Human IL-10 has cross-species actvity and is active on mouse cells. Mouse IL-10 is species-specific and does not act on human cells.
Uniprot IDP18893
Protein RefSeqNP_034678
mRNA RefSeqNM_010548

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