Mouse Anti-Human Dihydrofolate Reductase

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Size100 µg
Price350 €
CategoryMonoclonal Antibody
Clone Nr.(#24A8)
Species ReactivityHuman
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least for six months without detectable loss of activity.
AntigenRecombinant human Dihydrofolate Reductase
ApplicationWB, IHC (P), ICC
SynonymsDihydrofolate reductase
DescriptionDihydrofolate reductase (DHFR), also called dihydrofolic acid reductase, are enzymes that hydrogenate folic acid to dihydrofolic acid (DHF) and DHF to tetrahydrofolic acid (THF). These reactions activate the vitamin folic acid and are essential for nucleotide biosynthesis in all living organisms. In humans, DHFR is found in all tissue types. Mutations at the DHFR gene can cause dihydrofolate reductase deficiency, and this megaloblastic anemia.
Uniprot IDP00374
Protein RefSeqNP_000782.1
mRNA RefSeqNM_000791.3

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