Rat Anti-Mouse TIE-2, agonistic

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Cat-Nr.mT1002r-m
Size200 µg
Price520 €
CategoryMonoclonal Antibody
Clone Nr.(#MAB1201)
IsotypeIgG2
Species ReactivityCross reactivity to other species has not been tested!
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 400 µl sterile PBS and the final concentration is 500 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse extracellular domain of Tie2 receptor. The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized.
AntigenMouse Tie2 extracellular domain
ApplicationWB, Activation
SynonymsAngiopoietin-1 receptor; Endothelial tyrosine kinase; HYK; STK1; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; p140 TEK; CD202b; Tek; Hyk; Tie2; AA517024
DescriptionTie-2 is an endothelial-specific receptor tyrosine kinase and a receptor for angiopoietins. Tie-2 is predominantly expressed in the endothelium and it is likely involved in the regulation of vascular maturation and stability.
Uniprot IDQ02858
Protein RefSeqNP_038718.2
mRNA RefSeqNM_013690.2

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