E. coli Anti-Human FGFR-3 neutralizing antibody

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Cat-Nr.500-002
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.Recombinant IG
IsotypeFab-Fragment
Formulationlyophilized
BufferPBS
Stability and StorageLyophilized samples are stable for up to a year at -20 °C. Upon reconstitution, the Fab is stable for up to 1 month at 4 °C or up to 1 year at -20 °C.
SynonymsFGFR3; ACH; CEK2; JTK4; CD333; HSFGFR3EX
DescriptionFibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.
Uniprot IDP22607
Protein RefSeqNP_000133
mRNA RefSeqNM_000142

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