Rat Anti-Mouse Hedgehog interacting Protein (HIP)

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Cat-Nr.103-M231
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8L46)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of HIP extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigenrecombinant mouse protein of Hip EC-domain
ApplicationWB
Synonymshhip; hip; Xhip
DescriptionHedgehog-interacting protein )HIP) or Reg3B (regenerating islet-derived protein III beta; also PAPI) is a secreted, 17 kDa member of the Reg gene family, C-type lectin gene superfamily. It is found in pancreatic acinar cells, intestinal enterocytes and developing spinal motoneurons. Reg3B may play a role in intestinal epithelial cell renewal. It contains one C-type lectin domain. Mature mouse Reg3B is 91% and 67% aa identical to rat and human Reg3B, respectively.
Uniprot IDQ7TN16
Protein RefSeqNP_064655.4
mRNA RefSeqNM_020259.4

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