Mouse Anti-Human Chem R23

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Cat-Nr.101-M322
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6A30)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Chem R23.
Antigenhuman recombinant Chem R23
ApplicationFC
SynonymsCMKLR1; DEZ; ChemR23; CHEMERINR
DescriptionChemR23, also known as Dez in mouse, is a seven-pass transmembrane, G-protein-associated receptor related to the chemoattractant C3a and C5a complement receptors. Although it shows less than 30% amino acid identity to the chemokine receptor family, it shows significant structural similarity. ChemR23 expression is limited to macrophages and dendritic cells. A ligand for ChemR23 has been identified as Chemerin, also known as Tig-2. Receptor-ligand binding elicits chemotaxis of macrophages and immature, but not mature, dendritic cells.
Uniprot IDQ99788
Protein RefSeqNP_001135815.1
mRNA RefSeqNM_001142343.1

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