Rat Anti-Mouse IFN-gamma Receptor-1

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Cat-Nr.103-M234
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#7K23)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with purified mouse recombinant protein of INF gamma R1.
Antigenrecombinant mouse proteinof IFN-gamma R1
ApplicationWB, IHC (P)
SynonymsIfngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR; Interferon gamma Receptor 1
DescriptionThe high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta). Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.
Uniprot IDP15261
Protein RefSeqNP_034641.1
mRNA RefSeqNM_010511.2

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