Rat Anti-Mouse Cathepsin H

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Cat-Nr.103-M318
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#8J11)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of Cathepsin-H.
Antigenrecombinant human Cathepsin-H
ApplicationWB
SynonymsCtsh; AL022844
DescriptionCathepsin H is a lysosomal cysteine protease of the papain family (. It is synthesized as a precursor protein, consisting of a signal peptide (residues 1-20), a propeptide (residues 21-95), a mini chain (residues 96-103), a heavy chain (residues 114-290) and a light chain (residues 291-333). A truncated form with a 12 amino acid deletion in the signal peptide region is secreted. Cathepsin H is the only known monoaminopeptidase in the papain family. Cathepsin H expression is significantly increased in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.
Uniprot IDP49935
Protein RefSeqNP_031827
mRNA RefSeqNM_007801

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