Mouse Anti-Human CD83

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Cat-Nr.101-M316
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#4B34)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD83.
Antigenhuman recombinant CD8
ApplicationIHC, FC
SynonymsCD83; BL11; HB15
DescriptionCD83 is member of the Siglec family of transmembrane proteins. CD83 is a type I transmembrane glycoprotein that is a primary marker for dendritic cells. It also exists in multiple forms: membrane-bound CD83 is immunostimulatory while soluble CD83 is immunosuppressive. In the extracellular region, mouse and human CD83 are 66% identical at the aa level.
Uniprot IDQ01151
Protein RefSeqNP_004224.1
mRNA RefSeqNM_004233.3

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