Mouse Anti-Human CD102

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Cat-Nr.101-M287
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#7L4)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CD102 extracellular domain (also called ICAM-2).
AntigenHuman recombinant CD102 EC domain
ApplicationWB
SynonymsICAM2; CD102
DescriptionIntercellular adhesion molecule 2 (ICAM-2), also known as CD102, is a member of the immunoglobulin superfamily and binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.
Uniprot IDP13598
Protein RefSeqNP_001093256.1
mRNA RefSeqNM_001099786.1

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