Mouse Anti-Human Cripto

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Cat-Nr.101-M341
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6M17)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant Cripto-1.
Antigenhuman recombinant Cripto-1
ApplicationWB
SynonymsTDGF1; CR; CRGF; CRIPTO
DescriptionCripto, also known as TDGF-1 (Teratocarcinoma-Derived Growth Factor), is the founding member of the Epidermal Growth Factor-Cripto-1/FRL1/Cryptic Protein family of signaling proteins that function in cancer and various developmental processes. Mouse Cripto shares 66% and 34% amino acid identity with human Cripto and zebrafish one-eyed pinhead (OEP), respectively. Genetic evidence from mice and zebrafish points to a role for Cripto as an essential cofactor in Nodal signaling.
Uniprot IDP13385
Protein RefSeqNP_003203.1
mRNA RefSeqNM_003212.3

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