Rat Anti-Human CC Chemokine Receptor D6

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Cat-Nr.101-M159
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#25G14)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenRecombinant Human CC Chemokine Receptor D6
ApplicationFC
SynonymsACKR2, Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9
DescriptionThe D6 heptahelical membrane protein, expressed by lymphatic endothelial cells, is able to bind with high affinity to multiple proinflammatory CC chemokines. However, this binding does not allow D6 to couple to the signaling pathways activated by typical chemokine receptors such as CC-chemokine receptor-5 (CCR5).
Uniprot IDO00590
Protein RefSeqNP_001287.2
mRNA RefSeqNM_001296.4

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