Rat Anti-Mouse IL-17 receptor

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Cat-Nr.103-M245
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#10B27)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-17R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
AntigenMouse recombinant EC domain of IL-17R
ApplicationWB
SynonymsIl17ra; Il17r; Cdw217; VDw217; AW538159
DescriptionIL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R.
Uniprot IDQ60943
Protein RefSeqNP_032385.1
mRNA RefSeqNM_008359.2

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