Mouse Anti-Human FGF-17

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Cat-Nr.101-M405
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#5H27)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of fibroblast growth factor receptor 17.
AntigenRecombinant human FGF-17
ApplicationWB, IHC (P)
SynonymsFGF17; FGF-13
DescriptionFibroblast growth factors (FGFs) play multiple biological functions including angiogenesis, mitogenesis, cellular differentiation and wound repairing. All members of the FGF family have a conserved approximately 120 amino acid core with 30-70% identity. Among FGF family members, FGF17 is most similar to FGF8 (60% sequence identity) and FGF18 (50% sequence identity). The mRNA of FGF17 was found in midgestation of embryo and multiple adult tissues, and is preferentially expressed in specific sites, such as embryonic brain, developing skeleton and arteries. Human FGF17 shares 98.6% amino acid (aa) sequence identity with mouse FGF17. Rat FGF17 shares 100% aa sequence identity with mouse FGF17.
Uniprot IDO60258
Protein RefSeqNP_003858
mRNA RefSeqNM_003867

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