Mouse Anti-Human Fetuin-B

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Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#6N19)
Species ReactivityHuman
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant Fetuin-B.
Antigenrecombinant human Fetuin-B
SynonymsFETUB; 16G2; Gugu; IRL685
DescriptionFetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as α2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acutephase protein. Normal circulating levels of Fetuin A in adults (300-600 ug/mL) fall significantly (30-50%) during injury and infection. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were downregulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males.
Uniprot IDQ9QX79
Protein RefSeqNP_445800.1
mRNA RefSeqNM_053348.1

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