Mouse Anti-Human Complement MASP3

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Cat-Nr.101-M336
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#4F19)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Complement MASP3.
Antigenhuman recombinant Complement MASP3
ApplicationWB
SynonymsMASP1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1
DescriptionNine serine proteases and their cofactors participate in the three pathways that lead to complement activation. C1r and C1s are the first two proteases that trigger the classical pathway. Three mannan-binding lectin-associated serine proteases (MASPs) are involved in the MBL pathway. C2 is involved in both the classical and the MBL pathways. Factor D is the first protease that activates the alternative pathway, which also includes proteases factor B and factor I. C3 plays a central role in both classical and alternative pathways. C3d, one of its fragments, binds to CR2. C5 is common to all three pathways, and C5a belongs to a family of related proteins known as anaphylatoxins.
Uniprot IDP48740
Protein RefSeqNP_001027019.1
mRNA RefSeqNM_001031849.2

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