Rat Anti-Mouse Sclerostin
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Cat-Nr. | 103-M270 |
Size | 100 µg |
Price | 350 € |
Category | Monoclonal Antibody |
Clone Nr. | (#4D77) |
Isotype | IgG2 |
Species Reactivity | Mouse |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant Sclerostin. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Antigen | mouse recombinant protein of Sclerostin |
Application | WB |
Synonyms | Sost; 5430411E23Rik |
Description | SOST, also known as sclerostin, is a member of the Cerberus/DAN family of BMP antagonists, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is expressed by osteoclasts in developing bones of mouse embryos, including both intramembranously forming skull bones and endochondrally forming long bones. |
Uniprot ID | Q99P68 |
Protein RefSeq | NP_077769.3 |
mRNA RefSeq | NM_024449.5 |
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