Rat Anti-Mouse ADAM-19

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Cat-Nr.103-M302
Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#11J23)
IsotypeIgG2
Species ReactivityMouse
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of A Disintegrin and Metalloprotease-like Domain 19 ectodomain (ADAM19).
Antigenrecombinant protein of A Disintegrin and Metalloprotease-like Domain 19 ectodomain
ApplicationWB
SynonymsAdam19; M[b]; Mltnb; AL024287
DescriptionADAM-19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrinβ) is a 95-100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. After cleavage of a signal sequence and prodomain, the ectodomain circulates in plasma bound to α2 Macroglobulin. ADAM19 cleaves at sequences present in myelin basic protein, insulin β chain, TNFα, TRANCE and SCF. Over amino acids (aa) 205-705, mouse ADAM19 shares 87% aa sequence identity with human ADAM19.
Uniprot IDO35674
Protein RefSeqNP_033746.1
mRNA RefSeqNM_009616

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